I have the 22lr and I love it...looking for the mag used has been a chore. I don't want paper but 22 mags used for sale are rare...Good Luck...I would appreciate some opinions on how much I should pay for a used Ruger .22 Magnum LCR. I don't know much about pistols, although I do shoot a Mark III.
For self-defense use what ever you like if you reload the 327 lcr would make a better choice. I bought my wife the 22 mag she likes it but ammo is hard to come by three weeks after I got the 22 mag Ruger came out with the 327 just my luck.
The lcr .22wmr just may be the perfect cc gun-light, surgical precision and the best trigger pull in this class (don't believe me-grab a Smith .22wmr and see for yourself) ;
Lightweight, Compact Ruger LCR 22 Magnum Pocket Revolver