If you plan to CC this revolver, you'll want to practice with your defense ammo. You probably don't want to take it out and shoot 100 357 rounds through it. 38 ammo is most likely cheaper and not as hard on your hand.
Stick with a heavier round, like the 158 grain rounds and shooting it isn't really a problem. The only problem with shooting 38's in your .357 is that it will leave a carbon ring that can make it tough to load and/or extract .357 rounds. If you reload, you can tailor the round to your preferences. I kinda like the 158 grn lead FN round propelled by 6.5 grains of Bullseye.
There can be a carbon ring, and likely more so if you shoot cast boolits as I do. Have shot some thousands through our security six.
However, this is not a big issue.
By the time that happens, it is likely time to do a deep clean on the wheel gun any way, so take it apart, remove the cylindar and soak it over night in some Hoppies OR?? and the ring will very quickly clean out.
Finish cleaning and lubing the parts and put it back together and your good to go for many more shots.
All you need to do is load some .357 rounds in your cylindar and you will quickly know if there is a build up that needs to be removed.