Ruger made a .22 LR SP101, both the "original" 6 shot version and of course the new one.
If you want a DA .22 WMR revolver there are fewer choices, but a .22 LR DA like the SP101 or LCR is vastly cheaper to shoot. .22 WMR is surprisingly expensive.
This NAA Mini Master is a VERY high quality revolver, many people have 10's of thousands of rounds through them. They come with a LR and WMR cylinder, Millett sights and there are a ton of grip options. I have an NAA Mini .22 LR and it's one of my favorite guns.
There's also the PUG,.22 WMR with an available LR cylinder.......... it has XS tritium night sights or a plastic white dot (to lower the price) and is made for concealed carry.......one of these with the night sight is VERY high on my "needs" list!
These are out of stock right now, but for $300 you can get an alloy frame Czech made .22 WMR revolver........just gotta catch them when they have some.