With at least 95% of .22 pistols in stock configuration, I'd agree that reliability can be an issue. However, I believe the main problem is with the pistols themselves and not with the ammo. My mostly stock MKII has a failure rate of about 1/1000 rounds of common bulk ammo. But my optimized MKIII has over 30,000 consecutive rounds of the same ammo with ZERO failures. This reliability rate is certainly on par with (or better than) most centerfire pistols. But centerfire is normally more reliable out of the box.I sell guns for a living. The only reason I never suggest a .22 is the reliability of the ammo. I have had too many duds to rely on the ammo.