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Lexington1, After looking at your desired scope specifications, you will have to make some compromises.
Let's start with the reticle ... A Mil-dot is great for long range shooting, assuming you know how to use them. They are horrible for hunting and especially "close up" shooting ... way worse in low light levels. Your best choice for a reticle is a "dual X", which has thicker outer lines and thinner inner lines. In subdued light, fine cross hairs are nearly impossible to see. Illuminated reticles make the scope's turret fat so it may not fit between the rings unless you buy an extended base.
Next is parallax, which is a very significant negative aspect with any scope ... the higher the magnification, the worse it gets. Many people blame the gun or even the ammo for poor accuracy when it's likely a parallax issue. Rimfire scopes are typically corrected for 50~60 yards. The formula for maintaining 1" or less of cross hair drift is twice the parallax corrected distance for max range and half the parallax corrected distance for the closest range. The Nikon P-22 you mentioned is parallax corrected for 50 yards so it would be fine from 50/2=25 yards to 50*2=100 yards. At distances closer than 25 yards or more than 100 yards, cross hair drift becomes increasingly worse ... up to several inches. For target rifles, the best solution is a "side dial" or AO but for hunting rifles, these devices tend to corrupt the hunt. By the time you figure out the distance, adjust your magnification, then adjust parallax correction, the critter disappeared. It just gets too busy for these devices to work well.
Yes, at closer distances, your gun will shoot low. The higher the scope is mounted above bore line, the lower it will shoot at closer distances. Here's a 22 LR trajectory chart where the center of the scope lens is 1", 1.5", and 2" above bore line and the scope is zeroed for 50 yards:
I have a 10/22 TD and found my Nikon P-22 (2~7x) with the provided Ruger base works very well. I can get it in the backpack OK but the Velcro flap won't quite reach the pocket, due to the poor design of the short flap. No problem ... I went to Wally World and bought a roll of "sticky back" Velcro. I cut a couple 4" strips then stuck the "hook" piece to the "eye" piece. This makes a nice extension that will allow the flap to secure to the pocket. Because it is not sewed in, the extensions can easily be removed.
Here's an article I posted in the forum Library called "Scope Dope". It details the issues you may want to consider before buying a scope. Click on this link: http://rugerforum.net/library/61505-scope-dope.html
Let's start with the reticle ... A Mil-dot is great for long range shooting, assuming you know how to use them. They are horrible for hunting and especially "close up" shooting ... way worse in low light levels. Your best choice for a reticle is a "dual X", which has thicker outer lines and thinner inner lines. In subdued light, fine cross hairs are nearly impossible to see. Illuminated reticles make the scope's turret fat so it may not fit between the rings unless you buy an extended base.
Next is parallax, which is a very significant negative aspect with any scope ... the higher the magnification, the worse it gets. Many people blame the gun or even the ammo for poor accuracy when it's likely a parallax issue. Rimfire scopes are typically corrected for 50~60 yards. The formula for maintaining 1" or less of cross hair drift is twice the parallax corrected distance for max range and half the parallax corrected distance for the closest range. The Nikon P-22 you mentioned is parallax corrected for 50 yards so it would be fine from 50/2=25 yards to 50*2=100 yards. At distances closer than 25 yards or more than 100 yards, cross hair drift becomes increasingly worse ... up to several inches. For target rifles, the best solution is a "side dial" or AO but for hunting rifles, these devices tend to corrupt the hunt. By the time you figure out the distance, adjust your magnification, then adjust parallax correction, the critter disappeared. It just gets too busy for these devices to work well.
Yes, at closer distances, your gun will shoot low. The higher the scope is mounted above bore line, the lower it will shoot at closer distances. Here's a 22 LR trajectory chart where the center of the scope lens is 1", 1.5", and 2" above bore line and the scope is zeroed for 50 yards:

I have a 10/22 TD and found my Nikon P-22 (2~7x) with the provided Ruger base works very well. I can get it in the backpack OK but the Velcro flap won't quite reach the pocket, due to the poor design of the short flap. No problem ... I went to Wally World and bought a roll of "sticky back" Velcro. I cut a couple 4" strips then stuck the "hook" piece to the "eye" piece. This makes a nice extension that will allow the flap to secure to the pocket. Because it is not sewed in, the extensions can easily be removed.
Here's an article I posted in the forum Library called "Scope Dope". It details the issues you may want to consider before buying a scope. Click on this link: http://rugerforum.net/library/61505-scope-dope.html