Wow, I've never seen the like. It looks as though the bullets were never seated properly, although the top of the case looks as though it might have been crimped - maybe after the bullet was partially seated. I can't imagine that enough force could have been applied to them in the box to get them to "jump crimp" without also mangling the box.
As for shooting them...
My first concern would be that they'd be too long overall for the cylinder and would jam it. Assuming that the correct powder charge is in the case (kind of a guess, considering how the manufacturer clearly failed in QA), the peak chamber pressure should be slightly lower than normal, which might lead to incomplete combustion of the powder. The end result would be a low-power round, possibly even a squib if the factory also messed up the powder load.
Personally, I'd take these rounds - and probably the entire lot - apart and reload using the case and bullet. Considering the power of the .454 round, I wouldn't fire any round that looked "off", just in case there were hidden flaws, as well.
Jim